Heart Health is Now More Than Just “K”
There are many existing IDNutrition ingredients and formulas that are
beneficial for heart health, including Magnesium, Omega-3 Complex,
Vitamin E, COQ 10, Antioxidant Plus, L-Carnitine, Vitamin C, Ginkgo
Biloba and Vitamin D. Despite this, we thought we needed to more
specifically, develop a formula that provided support for the areas of
arterial stiffness, elasticity and circulatory system health. We achieved
this through the addition of the Heart Health formula, which includes Vitamin K2 (Menaquinone-7) and Grape Seed Extract (GSE).
In the past, medical science believed that calcification (calcium build-up in the dangerous plaque often found in the heart arteries) was an irreversible process and a result of aging. However, it is now known that calcium accumulation is an actively regulated process involving the Vitamin K-dependent Matrix Gla Protein (MGP), the most potent inhibitor of calcification known.
MGP acts as a calcium traf c cop and is actively involved in making sure calcium ends up in teeth and bones and not in arteries, where plaque buildup causing arterial stiffness has been attributed to increased risk of heart attack and stroke.
Healthy arteries have shown to contain 100 times more Vitamin K2 than unhealthy arteries and the amount of calcium in the arteries is a risk factor for cardiovascular health. One might say that “you are as old as your arteries.” Studies in large population groups show that significant calcification in young people actually makes them older than their chronological age. This could be a factor causing as many as 4-10% of all heart attacks to occur before age 45, and most of these strike men. With respect to chronological age, older people with little or no calcification may deduct up to 10 years from their actual age.
The Rotterdam Study (2004) shows that high dietary intake of Vitamin K2 – but not Vitamin K1 – has a strong protective effect on cardiovascular health. Findings from this 10-year population-based study, which followed 4,807 initially healthy men and women older than 55 years of age at the start of the study, indicate that eating foods rich in natural Vitamin K2 (at least 32 mcg/day) results in 50% reduction of arterial calcification, 50% reduction of cardiovascular risk, and 25% reduction of all-cause mortality.
Despite the results of this study and many others supporting the need for Vitamin K2, the Western diet does not contain sufficient Vitamin K2. Because of this, supplementing with Vitamin K2 in the form of MK-7 is a supplemental choice recommended by experts.
Consistent with past, present and future ingredient standards of IDLife, IDNutrition is using the more expensive and more effective Menaquinone-7 (MK-7) form of Vitamin K2 in this formula for maximization of these benefits.
Grape Seed Extract (GSE)
Consumption of red wine, red grape juice, grape skin and grape seeds has been linked to many health bene ts. In 2006, researchers pinpointed that compounds in red wine help relax circulation and that these compounds were highest in red wines from southwestern France and Sardinia, regions that are associated with increased longevity.
One of the two main grape phytochemicals responsible for heart health and other bene ts is Grape Seed Extract (GSE) with 95% Proanthocyanidins (PACs) as its major component. PACs are very strong antioxidants and GSEs are powerful cardioprotective compounds. They strengthen your arteries and capillaries and offer rather dramatic antioxidant protection for your arteries and heart. Through a number of mechanisms, they also reduce the likelihood that plaque will form in your arteries.
Recent molecular science shows that the effects of GSE are much more diverse than previously understood. GSE works actively to promote favorable changes to cardiovascular health, including helping to reduce inflammation and helping to improve cholesterol and triglyceride metabolism.
Even WebMD states “There’s strong evidence that grape seed extract is beneficial for a number of cardiovascular conditions. Grape seed extract may help with a type of poor circulation (chronic venous insufficiency) and high cholesterol. Grape seed extract also reduces swelling caused by injury and helps with eye disease related to diabetes.”
Proanthocyanidins from GSE are powerful protectors of your heart and general circulation. They positively change a number of metabolic signals toward reduced risk for cardiovascular disease and are proven to act as a water-soluble antioxidant. They also help lower key inflammatory signals such as TNF-alpha, CRP, and IL6.
The combination of Vitamin K2 (as Menaquinone-7) and Grape Seed Extract (95% Proanthocyanidins) is a powerful addition to the IDNutrition Heart Health arsenal.
The science would seem to support the concept that the combined ingredients would have a beneficial impact by supporting the body’s effort to:
This new formula will potentiate the existing beneficial heart nutrients we provide in IDNutrition for IDLife Associates, their families, and their customers.